# Publications CMI users agree to acknowledge the support of **"the Center for Macromolecular Interactions at Harvard Medical School*****"*** in publications arising from use of the facility. **CMI RRID: SCR\_018270.** - If a CMI staff member has made an important intellectual contribution to the project, as determined by generally accepted criteria for academic collaborations, then that person should be considered for authorship on the publication. - CMI users may [enter publications directly in the CMI PPMS system](https://ppms.us/hms-cmi/pub/) or email the Pubmed ID (or the reference) to . Sort & Filters close ## Filters Year of Publication expand\_more 2026 (13) 2025 (31) 2024 (31) 2023 (23) 2022 (16) 2021 (22) 2020 (24) 2019 (16) 2018 (26) 2017 (20) 2016 (20) 2015 (7) 2014 (3) Publication type expand\_more Book Chapter (1) Journal Article (217) Patent (1) Thesis (33) Search Within Results Search Within Results search ## 252 results Show filters filter\_alt Sort by Year of PublicationAlphabetical A-Z sort ## 252 results Download 252 citations download- [BibTeX](/node/1876436/export?format=bibtex) - [EndNote X3 XML](/node/1876436/export?format=endnote8) - [EndNote 7 XML](/node/1876436/export?format=endnote7) - [Endnote tagged](/node/1876436/export?format=tagged) - [Marc](/node/1876436/export?format=marc) - [PubMedId](/node/1876436/export?format=pubmed_id) - [RIS](/node/1876436/export?format=ris) ### 2026 Sirimanakul, Suwitchaya, Joseph D. Hurley, Nakarin Vutipow, Fabien Loison, Anongnard Kasorn, Lueacha Tabtimmai, Pinpunya Riangrungroj, Jeerapond Leelawattanachai, Teetouch Ananwattanasuk, Napachanok Swainson, Kiattawee Choowongkomon, Andrew C. Kruse, and Dujduan Waraho-Zhmayev. [2026] 2026. “[A Simple and Cost-Effective Electrochemical Assay for Heart Failure Prognosis Using Soluble Suppression of Tumorigenicity 2-Specific Nanobodies](/publication/simple-and-cost-effective-electrochemical-assay-heart-failure-prognosis-using-soluble)”. *ACS Pharmacology & Translational Science*. doi:10.1021/acsptsci.6c00082. Sirimanakul, Suwitchaya, Joseph D. Hurley, Nakarin Vutipow, Fabien Loison, Anongnard Kasorn, Lueacha Tabtimmai, Pinpunya Riangrungroj, Jeerapond Leelawattanachai, Teetouch Ananwattanasuk, Napachanok Swainson, Kiattawee Choowongkomon, Andrew C. Kruse, and Dujduan Waraho-Zhmayev. [2026] 2026. “[A Simple and Cost-Effective Electrochemical Assay for Heart Failure Prognosis Using Soluble Suppression of Tumorigenicity 2-Specific Nanobodies](/publication/simple-and-cost-effective-electrochemical-assay-heart-failure-prognosis-using-soluble)”. *ACS Pharmacology & Translational Science*. doi:10.1021/acsptsci.6c00082. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1021/acsptsci.6c00082) Heart failure (HF) is a major global health concern, particularly in low- and middle-income countries where it is often underdiagnosed. Prognostic testing plays a crucial role in guiding treatment and monitoring disease progression. In this study, we... - [ descriptionPublisher's Version](https://doi.org/10.1021/acsptsci.6c00082) de Puig, Helena, Erkin Kuru, Michaël Moret, Allison Flores, Suneesh Karunakaran, Dinara Sayfullina, Subhrajit Rout, Carmen Escobedo-Lucea, James J. Collins, and George M. Church. [2026] 2026. “[Genetic Code Expansion Enables Programmable Covalent Protein Design](/publication/genetic-code-expansion-enables-programmable-covalent-protein-design)”. *BioRxiv* (2026.05.15.725538). doi:10.64898/2026.05.15.725538. de Puig, Helena, Erkin Kuru, Michaël Moret, Allison Flores, Suneesh Karunakaran, Dinara Sayfullina, Subhrajit Rout, Carmen Escobedo-Lucea, James J. Collins, and George M. Church. [2026] 2026. “[Genetic Code Expansion Enables Programmable Covalent Protein Design](/publication/genetic-code-expansion-enables-programmable-covalent-protein-design)”. *BioRxiv* (2026.05.15.725538). doi:10.64898/2026.05.15.725538. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.biorxiv.org/content/biorxiv/early/2026/05/16/2026.05.15.725538.full.pdf) Covalent chemistry has transformed small-molecule drug discovery, yet analogous strategies for proteins remain largely inaccessible because covalent warheads cannot be readily integrated into biologics. Conventional genetic code expansion requires... - [ descriptionPublisher's Version](https://www.biorxiv.org/content/biorxiv/early/2026/05/16/2026.05.15.725538.full.pdf) Ragucci, Adelyn E, Sadie P Antine, Ethan M Leviss, Sarah E Mooney, Jasmine M Garcia, Lena Shyrokova, Vasili Hauryliuk, Amy S Y Lee, and Philip J Kranzusch. [2026] 2026. “[Nuclease-NTPase Antiphage Defence Systems Use Conserved Molecular Features to Control Bacterial Immunity.](/publication/nuclease-ntpase-antiphage-defence-systems-use-conserved-molecular-features-control)”. *Nature Microbiology*. doi:10.1038/s41564-026-02312-8. Ragucci, Adelyn E, Sadie P Antine, Ethan M Leviss, Sarah E Mooney, Jasmine M Garcia, Lena Shyrokova, Vasili Hauryliuk, Amy S Y Lee, and Philip J Kranzusch. [2026] 2026. “[Nuclease-NTPase Antiphage Defence Systems Use Conserved Molecular Features to Control Bacterial Immunity.](/publication/nuclease-ntpase-antiphage-defence-systems-use-conserved-molecular-features-control)”. *Nature Microbiology*. doi:10.1038/s41564-026-02312-8. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.doi.org/10.1038/s41564-026-02312-8) Bacteria encode diverse defence systems, including restriction-modification and CRISPR-Cas, that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstrate that many recently identified antiphage defence operons comprise a... - [ descriptionPublisher's Version](https://www.doi.org/10.1038/s41564-026-02312-8) Wijne, Charlotte, Pavana Suresh, Richard Dela Rosa, Luc van Oss, Sabine Normann, William McKibben, Florian I Schmidt, and Hidde Ploegh. [2026] 2026. “[Modulation of Ube2R1 Activity by a Nanobody That Binds Near Its N-Terminus.](/publication/modulation-ube2r1-activity-nanobody-binds-near-its-n-terminus)”. *The Biochemical Journal* 483(3):345-63. doi:10.1042/BCJ20250271. Wijne, Charlotte, Pavana Suresh, Richard Dela Rosa, Luc van Oss, Sabine Normann, William McKibben, Florian I Schmidt, and Hidde Ploegh. [2026] 2026. “[Modulation of Ube2R1 Activity by a Nanobody That Binds Near Its N-Terminus.](/publication/modulation-ube2r1-activity-nanobody-binds-near-its-n-terminus)”. *The Biochemical Journal* 483(3):345-63. doi:10.1042/BCJ20250271. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1042/BCJ20250271) Ube2R1 (Cdc34) is a K48-ubiquitin chain-specific ubiquitin-conjugating (E2) enzyme central to proteasomal degradation, yet the regulatory potential of its unique structural elements remains underexplored. Here, we report the isolation and biochemical... - [ descriptionPublisher's Version](https://doi.org/10.1042/BCJ20250271) Erdi, Metecan, Anujan Ramesh, Vinny Chandran Suja, Shuyang Zhang, Samir Mitragotri, and Bijay Singh. [2026] 2026. “[High Concentration Antibody Formulations Enabled via Thermostable Ionic Liquids.](/publication/high-concentration-antibody-formulations-enabled-thermostable-ionic-liquids)”. *Advanced Materials (Deerfield Beach, Fla.)* e11918. doi:10.1002/adma.202511918. Erdi, Metecan, Anujan Ramesh, Vinny Chandran Suja, Shuyang Zhang, Samir Mitragotri, and Bijay Singh. [2026] 2026. “[High Concentration Antibody Formulations Enabled via Thermostable Ionic Liquids.](/publication/high-concentration-antibody-formulations-enabled-thermostable-ionic-liquids)”. *Advanced Materials (Deerfield Beach, Fla.)* e11918. doi:10.1002/adma.202511918. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1002/adma.202511918) Concentrated protein formulations have garnered significant attention in both commercial and research domains due to their relevance in patient-favored, subcutaneous administration. However, these formulations face challenges such as high viscosity and... - [ descriptionPublisher's Version](https://doi.org/10.1002/adma.202511918) Valeriano, Manuel Osorio, Alexander C Stone, Masahiro Nagano, Bonnie Su, Laura Caccianini, Anders Sejr Hansen, Lucas Farnung, and Seychelle M Vos. [2026] 2026. “[Structural Basis for CTCF-Mediated Chromatin Organization.](/publication/structural-basis-ctcf-mediated-chromatin-organization)”. *BioRxiv : The Preprint Server for Biology*. doi:10.64898/2026.02.06.704447. Valeriano, Manuel Osorio, Alexander C Stone, Masahiro Nagano, Bonnie Su, Laura Caccianini, Anders Sejr Hansen, Lucas Farnung, and Seychelle M Vos. [2026] 2026. “[Structural Basis for CTCF-Mediated Chromatin Organization.](/publication/structural-basis-ctcf-mediated-chromatin-organization)”. *BioRxiv : The Preprint Server for Biology*. doi:10.64898/2026.02.06.704447. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.64898/2026.02.06.704447) Eukaryotic DNA is organized across multiple scales to support genome compaction, appropriate gene expression, and DNA recombination. A central player in these roles is the CCCTC binding factor (CTCF), which defines specific chromatin loop structures and... - [ descriptionPublisher's Version](https://doi.org/10.64898/2026.02.06.704447) Sockett, Kaitlynn A, Madeline K Loffredo, Christian D DeMoya, Zoe G Garman, and Mark W Grinstaff. [2026] 2026. “[Clickable Polyamidosaccharides: Accessing Bottlebrush Inspired Hyaluronic Acid Glycopolymers for CD44 Targeting of Breast Cancer Cells.](/publication/clickable-polyamidosaccharides-accessing-bottlebrush-inspired-hyaluronic-acid)”. *Biomaterials Science*. doi:10.1039/d5bm01613d. Sockett, Kaitlynn A, Madeline K Loffredo, Christian D DeMoya, Zoe G Garman, and Mark W Grinstaff. [2026] 2026. “[Clickable Polyamidosaccharides: Accessing Bottlebrush Inspired Hyaluronic Acid Glycopolymers for CD44 Targeting of Breast Cancer Cells.](/publication/clickable-polyamidosaccharides-accessing-bottlebrush-inspired-hyaluronic-acid)”. *Biomaterials Science*. doi:10.1039/d5bm01613d. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1039/d5bm01613d) Hyaluronic acid (HA) binds the transmembrane glycoprotein cluster of differentiation-44 (CD44), a highly expressed surface receptor that plays a critical role in tumor growth, invasion, and metastasis. Approaches to target CD44 utilize biologically... - [ descriptionPublisher's Version](https://doi.org/10.1039/d5bm01613d) Yamaguchi, Sonomi, Samantha G Fernandez, Douglas R Wassarman, Marlen Lüders, Frank Schwede, and Philip J Kranzusch. [2026] 2026. “[Nucleotide Signals Coordinate Activation and Inhibition of Bacterial Immunity.](/publication/nucleotide-signals-coordinate-activation-and-inhibition-bacterial-immunity)”. *Nature*. doi:10.1038/s41586-026-10135-0. Yamaguchi, Sonomi, Samantha G Fernandez, Douglas R Wassarman, Marlen Lüders, Frank Schwede, and Philip J Kranzusch. [2026] 2026. “[Nucleotide Signals Coordinate Activation and Inhibition of Bacterial Immunity.](/publication/nucleotide-signals-coordinate-activation-and-inhibition-bacterial-immunity)”. *Nature*. doi:10.1038/s41586-026-10135-0. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1038/s41586-026-10135-0) The cellular nucleotide pool is a major focal point of the host immune response to viral infection. Immune effector proteins that disrupt the nucleotide pool enable animal and bacterial cells to broadly restrict diverse viruses, but reduced nucleotide... - [ descriptionPublisher's Version](https://doi.org/10.1038/s41586-026-10135-0) Case, Brandon C, Leonardo Scoccia, Zhihan Zhao, and Joseph J Loparo. [2026] 2026. “[DNA Polymerase λ Autoinhibition Is Relieved via Ku Interaction During Non-Homologous End Joining.](/publication/dna-polymerase-l-autoinhibition-relieved-ku-interaction-during-non-homologous-end)”. *Nucleic Acids Research* 54(4). doi:10.1093/nar/gkag114. Case, Brandon C, Leonardo Scoccia, Zhihan Zhao, and Joseph J Loparo. [2026] 2026. “[DNA Polymerase λ Autoinhibition Is Relieved via Ku Interaction During Non-Homologous End Joining.](/publication/dna-polymerase-l-autoinhibition-relieved-ku-interaction-during-non-homologous-end)”. *Nucleic Acids Research* 54(4). doi:10.1093/nar/gkag114. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1093/nar/gkag114) DNA ends are frequently damaged during the formation of DNA double-strand breaks (DSBs). These ends must be repaired to enable ligation during non-homologous end joining (NHEJ). NHEJ uses several end processing factors to repair DNA ends within the short... - [ descriptionPublisher's Version](https://doi.org/10.1093/nar/gkag114) Sargen, Molly R, Sadie P Antine, Grzegorz J Grabe, Gabriella Antonellis, Adelyn E Ragucci, Yao Li, Philip J Kranzusch, and Sophie Helaine. [2026] 2026. “[A Prophage-Encoded Abortive Infection Protein Preserves Host and Prophage Spread.](/publication/prophage-encoded-abortive-infection-protein-preserves-host-and-prophage-spread)”. *Nature*. doi:10.1038/s41586-025-10070-6. Sargen, Molly R, Sadie P Antine, Grzegorz J Grabe, Gabriella Antonellis, Adelyn E Ragucci, Yao Li, Philip J Kranzusch, and Sophie Helaine. [2026] 2026. “[A Prophage-Encoded Abortive Infection Protein Preserves Host and Prophage Spread.](/publication/prophage-encoded-abortive-infection-protein-preserves-host-and-prophage-spread)”. *Nature*. doi:10.1038/s41586-025-10070-6. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1038/s41586-025-10070-6) Most bacterial pathogens are polylysogens, harbouring multiple vertically transmitted prophages. These prophages enhance bacterial pathogenicity and survival by encoding virulence factors and anti-phage defence systems while retaining the capacity for... - [ descriptionPublisher's Version](https://doi.org/10.1038/s41586-025-10070-6) Fisher, Robert J, Kihyun Park, Kwangwoon Lee, Katarina Pinjusic, Allison Vanasse, Christina S Ennis, Parisa Farokh, Scott B Ficaro, Jarrod A Marto, Hanjie Jiang, Eunju Nam, Stephanie Stransky, Joseph Duke-Cohan, Melis A Akinci, Anupa Geethadevi, Eric Raabe, Ana Fiszbein, Shadmehr Demehri, Simone Sidoli, Chad W Hicks, Derin B Keskin, Catherine J Wu, Philip A Cole, and Rhoda M Alani. [2026] 2026. “[CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity.](/publication/corest-complex-inhibition-alters-rna-splicing-promote-neoantigen-expression-and-enhance)”. *JCI Insight* 11(2). doi:10.1172/jci.insight.190287. Fisher, Robert J, Kihyun Park, Kwangwoon Lee, Katarina Pinjusic, Allison Vanasse, Christina S Ennis, Parisa Farokh, Scott B Ficaro, Jarrod A Marto, Hanjie Jiang, Eunju Nam, Stephanie Stransky, Joseph Duke-Cohan, Melis A Akinci, Anupa Geethadevi, Eric Raabe, Ana Fiszbein, Shadmehr Demehri, Simone Sidoli, Chad W Hicks, Derin B Keskin, Catherine J Wu, Philip A Cole, and Rhoda M Alani. [2026] 2026. “[CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity.](/publication/corest-complex-inhibition-alters-rna-splicing-promote-neoantigen-expression-and-enhance)”. *JCI Insight* 11(2). doi:10.1172/jci.insight.190287. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1172/jci.insight.190287) Epigenetic macromolecular enzyme complexes tightly regulate gene expression at the chromatin level and have recently been found to colocalize with RNA splicing machinery during active transcription; however, the precise functional consequences of these... - [ descriptionPublisher's Version](https://doi.org/10.1172/jci.insight.190287) Yu, Zishuo, Pradeep Sathyanarayana, Cong Liu, Joel M J Tan, Pan Yang, Biswajit Das, Side Hu, Xiaoyi Fan, Chenggong Ji, Sandra K Weller, Mrinal Shekhar, Donald M Coen, Philip J Kranzusch, Joseph J Loparo, and Jonathan Abraham. [2026] 2026. “[Mechanisms of HSV-1 Helicase-Primase Inhibition and Replication Fork Complex Assembly.](/publication/mechanisms-hsv-1-helicase-primase-inhibition-and-replication-fork-complex-assembly)”. *Cell* 189(2):478-494.e18. doi:10.1016/j.cell.2025.11.041. Yu, Zishuo, Pradeep Sathyanarayana, Cong Liu, Joel M J Tan, Pan Yang, Biswajit Das, Side Hu, Xiaoyi Fan, Chenggong Ji, Sandra K Weller, Mrinal Shekhar, Donald M Coen, Philip J Kranzusch, Joseph J Loparo, and Jonathan Abraham. [2026] 2026. “[Mechanisms of HSV-1 Helicase-Primase Inhibition and Replication Fork Complex Assembly.](/publication/mechanisms-hsv-1-helicase-primase-inhibition-and-replication-fork-complex-assembly)”. *Cell* 189(2):478-494.e18. doi:10.1016/j.cell.2025.11.041. - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1016/j.cell.2025.11.041) Herpesviruses are widespread double-stranded DNA viruses that establish lifelong latency and cause various diseases. Although DNA-polymerase-targeting antivirals are effective, increasing drug resistance underscores the need for alternatives. Helicase... - [ descriptionPublisher's Version](https://doi.org/10.1016/j.cell.2025.11.041) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [ Last page 21 ](?page=20 "Go to last page") - [ Next page chevron\_right ](?page=1 "Go to next page")