In response to the COVID-19 pandemic, the CMI is closed for general access as of March 19, 2020. See the latest guidelines from Harvard Medical School (https://hms.harvard.edu/coronavirus) for more information. If you are doing COVID-19 research and require access to CMI instrumentation, contact Kelly Arnett at email@example.com. Remote consultations can be requested through PPMS or by contacting firstname.lastname@example.org. Stay safe!
HMS Phase 2 Re-Entry
Harvard Medical School is actively planning a phased re-opening of the campus and research laboratories, under social distancing restrictions. The school has not released a timeline for re-entry. Likewise, CMI plans for re-opening are being refined and could change. Our current plan is to begin opening up to the HMS community in stages, when (or shortly after) HMS transitions to phase 2. The first priority will be to support instrument access by previously-trained HMS-affiliated CMI users. At least for the first several weeks of the ramp-up we will not be training new users at the CMI. We need to figure out how to do that safely and, initially, will focus on accommodating the needs of current users with ongoing projects.
Center for Macromolecular Interactions
Welcome to the Center for Macromolecular Interactions (CMI) in the department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. Our mission is to enhance basic research in the HMS community by providing scientific consultation, training and access to shared biophysical instruments for the characterization and analysis of macromolecules and their complexes.
The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Light Scattering: size-exclusion chromatography with multi-angle light scattering (SEC-MALS) and Dynamic Light Scattering (DLS), and MicroScale Thermophoresis (MST).