The CMI is in Phase 2 Re-Entry, as of Monday, June 15. The CMI COVID-19 Plan summarizes the changes implemented at CMI to maintain social distancing, enhance safety and accomodate as many users as possible.
All existing CMI Users must submit a CMI COVID-19 Re-entry Form to regain instrument access. Trained academic CMI users from local institutions who have submitted this form will be able to book instruments at that time.
New Users should request an account at the CMI, but note that all training is being deferred at this time.
Center for Macromolecular Interactions
Welcome to the Center for Macromolecular Interactions (CMI) in the department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. Our mission is to enhance basic research in the HMS community by providing scientific consultation, training and access to shared biophysical instruments for the characterization and analysis of macromolecules and their complexes.
The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Light Scattering: size-exclusion chromatography with multi-angle light scattering (SEC-MALS) and Dynamic Light Scattering (DLS), and MicroScale Thermophoresis (MST).