Center for Macromolecular Interactions
Welcome to the Center for Macromolecular Interactions (CMI) in the department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. Our mission is to enhance basic research in the HMS community by providing scientific consultation, training and access to shared biophysical instruments for the characterization and analysis of macromolecules and their complexes.
The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography for Multi-Angle Light Scattering (SEC-MALS) or Fluorescence detection (FSEC), and MicroScale Thermophoresis (MST). To learn more about technologies available, go to the CMI Instruments Page.