Fees

• Users from labs with a primary appointment at Harvard Medical School or Harvard University are charged the base academic rates.  
• Users are in this group if:
  • Harvard University administers the laboratory's grants  AND
  • the lab has a 33-digit code for internal billing

• Instrument	Access Fees (includes F&A)	One-time per-person Training Fees
  SPR: Biacore T200	$504/day	$648
  ITC: Microcal ITC200	$504/day	$648
  MST: NanoTemper Monolith NT.115	$62/hour	$459
  BLI: ForteBio Octet RED384	$62/hour	$459
  BLI: ForteBio BLItz	$62/hour	$306
  CD: Jasco J-815 CD	$50/hour	$396
  DSF: Life Tech. Quant Studio 6	$50/hour	$396
  DSF: NanoTemper Prometheus NT.Plex	$50/hour	$396
  Light Scattering: Wyatt DynaPro Plate Reader III	$50/hour	$396
  Light Scattering: Wyatt/Agilent SEC-MALS	$31.5/hour†  $504/day (max)	$648
  Mass Photometry: Refeyn TwoMP	$62/hour	$420
  Initial consultation	no charge

^† The SEC-MALS/FSEC system is billed in 4 hour blocks.

• Users from all non-Harvard academic labs are charged an additional Facilities and Administration Fee (F&A Fee) which goes to HMS to cover a portion of the facilities and administration costs for the CMI space.  The current F&A rate is 22%.
• Academic Users are considered External if:
  • their lab's grants are managed by any institution other than Harvard University
  • their lab will NOT be paying with a Harvard 33-digit billing code
  • their lab is located at a affiliated Hospital (including BWH, Children's Hospital, Beth Isreal, DFCI, MGH) or other academic institution 
• Users from academic institutions not affiliated with Harvard or Harvard Medical School will need to provide a PO number before access.

^† The SEC-MALS/FSEC system is billed in 4 hour blocks.

• Non-academic access is granted on a case-by-case basis, by the CMI director. 
• Priority access is given to Harvard-affiliates and academic users. 
• Users from non-academic institutions will need to provide a PO number before access.
• Harvard Life Lab companies are offered a 25% discount off the standard commercial rates.

For more information or to inquire about access, contact cmi@hms.harvard.edu.

^† The SEC-MALS/FSEC system is billed in 4 hour blocks.

Data Collection Fees

• Limited Data Collection Services are offered. Service fees will be charged for all completed services, regardless of experimental outcome. 
• Before submitting samples for data collection, users must approve the estimated charges and be given a date and time for sample delivery.
  • External Users will also be required to submit a PO and a signed CMI User Agreement.
• Most CMI Data Collection Services include a setup fee plus a per-sample data collection fee. Some services include one or more replicate measurements by default in the sample fee (e.g. DLS and DSF). For others, there may be reduced-price replicate measurement fee (e.g. SEC-MALS and CD) if collected in the same dataset.

Data Collection Fee List

Example project details: Light Scattering analysis project for SEC-MALS of 2 proteins in one buffer system. Project setup includes column equilibration (12+ column volumes) into user-provided buffer and a BSA control experiment.  One additional replicate injection of each sample was requested.

Please contact the CMI to start a conversation about nanobody selections.  Fees for Nanobody selections cover supplies and labor and are assessed for completed stages in the selection, regardless of final experimental outcome of the selection.