All Equipment

Spark Multimode Plate Reader from Tecan, configured with Absorbance mode, Luminescence mode, and enhanced Fusion Optics Fluorescence mode.  

The eProtein Discovery system from Nuclera is a platform for Cell-Free Protein Synthesis (CFPS), or in vitro transcription/translation, and enables rapid protein prototyping on a digital microfluidic chip. 

The TwoMP from Refeyn for Mass Photometry is a single-particle static light scattering detector, used to measure molar mass in solution.

The DynaPro Plate Reader III from Wyatt detects Dynamic Light Scattering, used to measure hydrodynamic radius (R_h) of particles in solution.

Size Exclusion Chromatography with Multi-Angle Light Scattering is used to measure weight-averaged masses (M_w) of macromolecules in solution by measure the intensity of scattered light and concentration of a sample as it elutes from an SEC column.  The...

The Jasco J-1500 measures Circular Dichroism and can be used to measure protein secondary structure and thermal stability.

The Prometheus NT.plex from NanoTemper and the QuantStudio from Life Technologies detect Differential Scanning Fluorimetry, used to measure protein thermal stability.

The Biacore T200 from Cytiva, detects Surface Plasmon Resonance, an optical technique used to measure binding kinetics and binding equilibrium.

The Octet RED384 and BLItz instruments from Sartorius detect Biolayer Interferometry, an optical technique used to measure binding kinetics and binding equilibrium.

The Monolith NT.115pico from NanoTemper detects MicroScale Thermophoresis, movement in a temperature gradient, used to measure binding equilibrium.

The Agilent Infinity 1260 system with fluorescence and UV detectors is used for Analytical and Fluorescent Size-Exclusion Chromatography (fSEC), separation of proteins by size.

The AKTA Pure from Cytiva is a preparative liquid chromatography system, used for protein purification by Size-Exclusion Chromatography and Ion Exchange.