CD Services

CD Service

In addition to instrument training, the CMI is now offering basic protein Circular Dichroism Data Collection services, including Far-UV scan and thermal denaturation experiments.

CD Service Overview

Circular Dichroism (CD)

CMI CD Instrument: Jasco J-815

Protein Far-UV Scan for Secondary Structure Analysis
- this will strictly be a data collection service and analysis using CD deconvolution algorithms (e.g. Dichroweb) will be left to the user.
Protein Thermal Stability (fixed wavelength variable temperature measurement)

Data Collection Fees Summary

Data Collection Fees

Limited Data Collection Services are offered. Service fees will be charged for all completed services, regardless of experimental outcome.
Before submitting samples for data collection, users must approve the estimated charges and be given a date and time for sample delivery.
- External Users will also be required to submit a PO and a signed CMI User Agreement.
Most CMI Data Collection Services include a setup fee plus a per-sample data collection fee. Some services include one or more replicate measurements by default in the sample fee (e.g. DLS and DSF). For others, there may be reduced-price replicate measurement fee (e.g. SEC-MALS and CD) if collected in the same dataset.

Data Collection Fee List

CD Data Collection Fees

	Harvard base price	Non-Harvard (+F&A)	Commercial	Life Lab
CD scan set up fee Setup fee per dataset (up to 20 scans), includes 1 buffer control. Additional buffers should be listed as samples.	$190	$231.80	$463.60	$347.70
CD scan for secondary structure Per sample, Far-UV 260-185 nm scan, 5-10 accumulations, in addition to setup fee.	$120	$146.40	$292.80	$219.60
CD replicate sample scan Replicate sample collected in the same dataset (or alternate temperature scan of existing sample)	$60	$73.20	$146.40	$109.80
CD thermal melt Per sample, 20-95C scan, 1C interval, 1C/min rate, 30s hold, 1-3 wavelengths, includes CD scan at 20C.	$510	$622.20	$1,244.4	$933.30

Data Collection Services!

In 2022, the CMI launched data collection services for assessing protein quality and sample biophysical properties. To start a conversation about a data collection services project, please contact the CMI or send a Sample Form to cmi@hms.harvard.edu.

Required Service Forms:

Sample Form, for gathering sample details to aid in data collection. You may exclude proprietary information in your preliminary form (we'll let you know if essential information is missing).
Academic Services Agreement, for EXTERNAL academic data collection service users
OR Industry Services Agreement, for industry data collection service users