In addition to instrument training, the CMI is now offering basic Light Scattering Data Collection services, including:
For proteins and protein complexes at least 30 KDa, without high molecular weight modifiers (modifiers of mass >5% total).
For AAVs (replication-incompetent, ~3-5 MDa). Requires Empty Capsid control, provided by the user.
CMI SEC-MALS System: Wyatt Dawn Heleos with in-line DLS, RI UV, Agilent chromatography
CMI DLS Instrument: Wyatt Dyanpro Plate Reader III
For proteins and biopolymers up to 1000 nm in diameter. Includes:
The CMI offers data collection services for assessing protein quality and sample biophysical properties. To start a conversation about a data collection services project, please contact the CMI or send a Sample Form to cmi@hms.harvard.edu.