DSF Services


In the coming year, the CMI is preparing to add data collection services for assessing protein quality and sample biophysical properties.  The precise services to be offered and timeline are still in flux.

If you would like to be notified when CMI services are offered, share you opinions on which services you'd like to see provided, or to learn more, please contact the CMI.


DSF Service Overview

Differential Scanning Fluorimetry (DSF) with fluorescent dye or using intrinsic protein fluorescence

CMI DSF Instruments: Life Technologies Quant Studio 6/7 and NanoTemper Technologies Prometheus NT.Plex

  • Conventional DSF, protein thermal stability using hydrophobic dye Sypro Orange
  • NanoDSF, protein thermal stability using intrinsic protein fluorescence
  • Chemical denaturation
  • Buffer optimization by conventional DSF or NanoDSF